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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6946bc365fb5fadf55c93c09965775f0e3e575943ed1349a4470f2c063e77b6c' 
  AND token = 'zXLvLNTYWQI27k6wtAntDjilo8zQN/Oe+BHgWOD2BaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}