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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbefc390f8ec461d306e6e7c43026eb134f505322d8f2cc29919c20a92a80e36' 
  AND token = 'J/O18cZHxSiEWUVHbvliHH1xXA/QJqmM8BTqbVtVbCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}