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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '129b181c1e5401e7a88d861fc1cf1dbd872528f7ad044b7d3b12ed490014215d' 
  AND token = 'RNjZPZIxYGztmMS+guZA3sFfgDyH18//N0ZoueSbyWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}