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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b728ba789d9deffa2e66606be6ec98b09ae36c3481a3167759e3c8da13d3d4c' 
  AND token = 'hLB27rQkyiz0bW5lDSq8/j8etH8ixaO9UBCsqA7iiU4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}