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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '449c2ef13952d136f1e2764e379b6af19677fc2115216c0b3063e4af66896628' 
  AND token = 'Ad3F8NQ2O7j5m0rbtmmSnxX49NbX7kJ47ai3HggHpHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}