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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caf23ab7e22e8f06afe326297d487075660d9e068f849a8dade6351780d410be' 
  AND token = 'R4T6CFUvHBb3b1z3zKWcIqVXvgLMQgqghd07HF+2i+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}