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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd61e8f268443561762a4b1880768e5e781358dcd974245672fec0e647f7b47e9' 
  AND token = 'HRrc7Zxex+iYAwe7TaPORlUwSpQKcEa1zL740I0AU40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}