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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a942602e48a832e2714211c8ae05175b0e29c311061e978dabfdb532cba1cb27' 
  AND token = 'L8Rty/HNA+QzUzsYOiTZm+BUmfGNtAZQiQvxMDsXDok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}