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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7c6b69229cf8222a1b072d6f60e375f7954acc0fa59d6317a6fe0a939622e1d' 
  AND token = 'uHpXIfRXiY65ekPCjh4u7tZ4F3PWqYynoK3EAOOG/Wk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}