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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1026a11b80f58d302f24ad6dde97974b8bd24521be98db1c2282af2a20540591' 
  AND token = 'KPXobqJYeOn8JvZtiIkaoyKDdV167LlgUuWbmN7uc7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}