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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c0e72bc6fceaf61c5f3c2761ff7b60773e249839ea2626054358a52e7da141c' 
  AND token = '5ZtiMMmeTqRdsFrRF9n4BTSzU8fIKXhoKOBIF9sdjcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}