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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64643e588fd5b24cf6deca011cd28dff0c908599a755407ac620d7086f789ac2' 
  AND token = 'hEh9+pXdvgvZXPetiqiUqug1FTctAtcQYx41znldElY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}