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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26722532cd86982d80d834c672d6c2a84f20c24470276157e2911eb127bcfae6' 
  AND token = '2SNdem57rxYD6JJmz3PcS2hK4wnwSf9rppyQpK5XCow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}