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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6206925534ce0b80aa716caa3ed07bafb2a3bd86cf50ac128e843bf2a256725' 
  AND token = 'p+M08nMcRN5UCshjb2SeTp7AQ4Nt7Vd+kAzEayuR8BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}