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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1674f59d44ac3d6c49ff046c9cf2ee66f0fd4b80e6fa8381dcdf0542d105db1' 
  AND token = 'sEZm0CWbFDLslHlpmDX7QvL5CDxlXOSGy/P+Tk2i4fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}