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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457024c474c546e3091df850e603c708d331ff1f06ac3ad7062a88de937f9ce0' 
  AND token = '3lrd5rRRc1Gr5m5msfTFMWZT1adu5QDXcteDac/ZOH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}