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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6788a0c58ab57bdaf04d88056024a971a69bb7a11651cc82a40d4ded85f8d1a' 
  AND token = '3SwjsgnxT86xLIqfToOI8xDXSknM9899k3BATbZM9xQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}