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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba51cb00e7a4c30a0e2bb56dc2c27bc1467980cf005552846e533436b5789e5d' 
  AND token = 'dsmBgNX/z5jzqIKUNKbwGY8nIpXTVyWe5zjyA2ZQETs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}