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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33ac288980a40673fb788b04d395d4f6d7f132f352e3d8bf4c31777250e22589' 
  AND token = 'NEVHyDQUJkwaB3a+kzC+jRQDQOfI5mUT6IWRvC4CIC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}