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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '450b2667b3e53852ecbc862cb3b2f79e42b6bc0a49fd1669e32fc9df418a96bc' 
  AND token = 'dKV3i6sJ9/KfUYLEeH3OslAmTWi9pn0WwhOUqSz9WH4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}