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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed9da29b10b3f892a96652c97311dc7b43f528ec0fc2b390a35aae682affce9c' 
  AND token = '/+9i6/QPqaAtxGeaP/TYiTtLyYZhVkFXdtfFS/wTYH8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}