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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb2fa99e2de4a52ef63e81c6860165e542d1de666081039ce3c9c4ae1572464c' 
  AND token = 'e6d0Wf+nBDFv853Y2Bd8zw+4Q4VaqB9MWgzTTEN7zmM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}