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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca5bce693b5a722041731cf3226d28b48895336ad44a050bdb856a08f74b4945' 
  AND token = '3RzVcvSIoYR6kDWYW2CrkB2BvvWwpU7MwxB2N7Rbu4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}