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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d1ba25826ba36c071c05d2e8357e5435ed8fd4a67fdde18fcd44e26eb012718' 
  AND token = 'XL3UAdmUUgYDQdh9ELvZntnuP1VmiY27Q4gqvLDYpfM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}