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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746797c465fb8cb1680a5afb5978c28cbce262b547cf3547e06163efee695d4f' 
  AND token = 'JZA0Y0D7+2trQtl5W4O9U6lV3IMEQjMvDdxiNJ3AtXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}