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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af48237df35f2828b45706e9cb8cc6a6595807d869f079e7830fe1ac58d20d26' 
  AND token = 'HoNYYV8HbkdL3GjSGq6JOY15tk+JWqV9ksnlYmWloIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}