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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c8fd8a892a005598fac76b2a1d506731c1d456c1a608f4938582d8a7f04145c' 
  AND token = 'MDhqfcyaNnL4Pi6iTfrdjG4DXWQ7KN+JTKbg+iKPZD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}