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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a484b6c964a1b371b3d6ad1b83ee4b2026ce9398fc9da85a8ace16a5414850e8' 
  AND token = 'JxdV3PvxkTJ0gcseoCe/dAAb1GqPmJgFZADGS8nFH8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}