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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8eb274acf32fc0f079c0af42daafec5b831ed68c8110ade8dd2d0b2f16e330cf' 
  AND token = 'V7k7t9LzbHWia76ZgEVc5Lmv+RNGceugUpp86oJ1AFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}