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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb10c9b7054fc5fc3f3d75e5a07279814aa9aa5b5df20081aeee6f66c2d39ce' 
  AND token = 'QV+oJGMt8OFXI/NOVdz9MTU9+wMTvXeLaCO/5z955yA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}