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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7901ecdcb3599bb27ad745fb4d8062481dec137318e96a434db6261fe7b23bee' 
  AND token = 'ywkzlCepl/YwBB1m5vJWTudSNCmeUH6ek/L7UlxM56M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}