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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ae66e78070b715ea4863600b2639df34f45d99469096edfba0de54b46156453' 
  AND token = 'w3jZH5U6IavJI6mlaXKGfnA723do7sDEEbLLs8jvpHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}