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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0158d80805b59258bd68ab3a3fd6b2deb641de4a364f7ded38a7880608b9392' 
  AND token = '8liDREKCsF+AfisOQ6jyUb2am81rjC5hQLfkOqE9vE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}