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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5006539425b8c7fe4a22fcefb3f71edb87423de3c4062974ed6476ba21b70b69' 
  AND token = 'IyTbDxzTrkm/IndXcNWUzp3X8QDCZBFEOhF5l4ROG9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}