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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ecf6a38811c8e3e123586e7ad7ce3738103627708974d007e96af1830463da4' 
  AND token = 'mMRg3OonMhT8lv0X7HPeZIPB0Y7kDKT9CIokz7WVNMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}