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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14a64d6a4577015f8a7b2783a3033bb7f66d7761fac718793340a22d27d72b80' 
  AND token = 'yjNA5w0Sqav64S63KCESWXANqsz+kMZDAqASZ5/GamM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}