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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd659ec3b846b5cc385e88b5bd5045889be07a6f9466a39ccfe3587aa648bb189' 
  AND token = 'TTWImUfr8IL47hG7PTignPoyPulmykZd1ZMmRst8RwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}