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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497e68df7dfa2df393b673e54d63fbd562dcf1dc7e6eac2148f51ebb400c606a' 
  AND token = 'zjIhbJHZrIgUJC+TYC3OPR2fh7+tM/AnDtNSLxYtUf0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}