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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2475fd8db49d57047794b59846e7328da14b9d52162ca699310120c1bfa2e1e5' 
  AND token = 'ocZRONM0ykcRDGHBggGoelBCUMjkPNEtWouJw9M35gM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}