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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b8972381d7c6a5d04454fa7ea6d8e573c335509adc111cbc46a5db5639d5286' 
  AND token = 'KSqISrCd03kC6d2vycY0NJ7N0gy4tdY60MtF1GjTQUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}