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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df39188d852de5dcb30b688a6ef28439caa6dd83ffd63225cb7155a9158ad521' 
  AND token = 'gNRQlVL++D30Jz9xty69NnqEEaciNdJ1AQv/Dw4XHZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}