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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c6515e026841fe1e60501c1ca83a9e82189dfc79b2baebffa0781679a2c6407' 
  AND token = 'PxytoAt63OeQbTqLoZFTx5RMsVlGXPCvCy7IueWUiFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}