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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a429b3c60832391b6c3ac28d37b69a2e4f3f1c6a22b18398b588f19c435df121' 
  AND token = 'vc5RfoLKiRUdKXrQD87e/euHps3GWvwaMJHrYswQDHk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}