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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429efd3357b89d10dbe6f3b93bbf87e34167a0cb2643c2e83f104ff33070f4e4' 
  AND token = 'wBMNox7BFFwCcDywfaaLWOVfciFgkaD19sVjnFVfTUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}