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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e1d7100fcd485fe981938c5972c38edd9a9c794b4cacfe5ee85df3a11ec3d44' 
  AND token = 'ig8vm7uGEpPGWu54rkmKnj8sShjlEC4uDsDmNJ6cp2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}