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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '540b4e0e0551ec8d71ac8dbb22ad116ed41aed0e4994a0995a3df7a0a5dcef82' 
  AND token = 'ZDwe4zz1t0h+nOejEtDVC8ovIhBzOZZBoc66KGPC0Lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}