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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0301587b37c3d983be8954c8fe3ddea0600df3399cf9121ef80a0ffc86a225cd' 
  AND token = 'Qy68WQoVk4/Nl7DPJYN8ATxwa3AbVkEnibSKxLb+LCQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}