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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '726c87fb6c52abc592b25b2e801af32ff065ad397ea282938266a06ede8aa46f' 
  AND token = 'TZ3CvN4yyANi9NQ91L/ctdXhPc7s6iuWrTLRfXxu7WY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}