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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0adca995194ebd1e7b2e251f3cc9cd75541d8f5d736aef9fe60e3a001cd8267f' 
  AND token = 'K+kTaoqGCACQSWw1dT0aIPYK5dnlWTp+kI5X+CgGeuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}