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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ec7762b45c458e7ad0d97ceb8a7dcc1f256df764cd71f92c1b0f27d70d6b1e8' 
  AND token = 'jeWxzZsLb8rqyOI4MRR3ZjTPOZHqkHnA0fivBOPysF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}